Does CLOZAPINE Cause Pancytopenia? 227 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 227 reports of Pancytopenia have been filed in association with CLOZAPINE (CLOZAPINE). This represents 0.2% of all adverse event reports for CLOZAPINE.
227
Reports of Pancytopenia with CLOZAPINE
0.2%
of all CLOZAPINE reports
17
Deaths
131
Hospitalizations
How Dangerous Is Pancytopenia From CLOZAPINE?
Of the 227 reports, 17 (7.5%) resulted in death, 131 (57.7%) required hospitalization, and 33 (14.5%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOZAPINE. However, 227 reports have been filed with the FAERS database.
What Other Side Effects Does CLOZAPINE Cause?
Neutropenia (18,981)
Hospitalisation (12,144)
Death (9,500)
Schizophrenia (3,991)
White blood cell count decreased (3,454)
Off label use (3,192)
Neutrophil count increased (3,125)
Drug ineffective (3,105)
Neutrophilia (3,105)
White blood cell count increased (2,988)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which CLOZAPINE Alternatives Have Lower Pancytopenia Risk?
CLOZAPINE vs CLOZARIL
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTEIN C\PROTEIN S HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX HUMAN\COAGULATION FACTOR VII HUMAN\COAGULATION FACTOR X HUMAN\PROTHROMBIN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN
CLOZAPINE vs COAGULATION FACTOR IX RECOMBINANT HUMAN\ISOPROPYL ALCOHOL