Does COBIMETINIB Cause Hepatitis? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Hepatitis have been filed in association with COBIMETINIB (Cotellic). This represents 1.0% of all adverse event reports for COBIMETINIB.
40
Reports of Hepatitis with COBIMETINIB
1.0%
of all COBIMETINIB reports
0
Deaths
17
Hospitalizations
How Dangerous Is Hepatitis From COBIMETINIB?
Of the 40 reports, 17 (42.5%) required hospitalization, and 3 (7.5%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for COBIMETINIB. However, 40 reports have been filed with the FAERS database.
What Other Side Effects Does COBIMETINIB Cause?
Diarrhoea (412)
Off label use (411)
Rash (369)
Pyrexia (332)
Death (231)
Nausea (206)
Fatigue (198)
No adverse event (178)
Vomiting (168)
Acute kidney injury (133)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which COBIMETINIB Alternatives Have Lower Hepatitis Risk?
COBIMETINIB vs COCAETHYLENE
COBIMETINIB vs COCAINE
COBIMETINIB vs COCOA BUTTER\PHENYLEPHRINE
COBIMETINIB vs COD LIVER OIL
COBIMETINIB vs CODEINE