Does CODEINE Cause Adrenal insufficiency? 47 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 47 reports of Adrenal insufficiency have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 0.2% of all adverse event reports for CODEINE.
47
Reports of Adrenal insufficiency with CODEINE
0.2%
of all CODEINE reports
6
Deaths
23
Hospitalizations
How Dangerous Is Adrenal insufficiency From CODEINE?
Of the 47 reports, 6 (12.8%) resulted in death, 23 (48.9%) required hospitalization, and 6 (12.8%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
Yes, Adrenal insufficiency is listed as a known adverse reaction in the official FDA drug label for CODEINE.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which CODEINE Alternatives Have Lower Adrenal insufficiency Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE