Does CODEINE Cause Constipation? 523 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 523 reports of Constipation have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 2.4% of all adverse event reports for CODEINE.
523
Reports of Constipation with CODEINE
2.4%
of all CODEINE reports
119
Deaths
132
Hospitalizations
How Dangerous Is Constipation From CODEINE?
Of the 523 reports, 119 (22.8%) resulted in death, 132 (25.2%) required hospitalization, and 17 (3.3%) were considered life-threatening.
Is Constipation Listed in the Official Label?
Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for CODEINE.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which CODEINE Alternatives Have Lower Constipation Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE