Does CYTARABINE Cause Aplasia? 229 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 229 reports of Aplasia have been filed in association with CYTARABINE (cytarabine). This represents 0.5% of all adverse event reports for CYTARABINE.
229
Reports of Aplasia with CYTARABINE
0.5%
of all CYTARABINE reports
69
Deaths
129
Hospitalizations
How Dangerous Is Aplasia From CYTARABINE?
Of the 229 reports, 69 (30.1%) resulted in death, 129 (56.3%) required hospitalization, and 43 (18.8%) were considered life-threatening.
Is Aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 229 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Aplasia?
ETOPOSIDE (217)
CYCLOPHOSPHAMIDE (213)
METHOTREXATE (199)
VINCRISTINE (167)
DOXORUBICIN (144)
CARBOPLATIN (136)
DEXAMETHASONE (129)
RITUXIMAB (98)
IFOSFAMIDE (88)
FLUDARABINE (80)
Which CYTARABINE Alternatives Have Lower Aplasia Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB