Does CYTARABINE Cause Differentiation syndrome? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Differentiation syndrome have been filed in association with CYTARABINE (cytarabine). This represents 0.1% of all adverse event reports for CYTARABINE.
33
Reports of Differentiation syndrome with CYTARABINE
0.1%
of all CYTARABINE reports
4
Deaths
23
Hospitalizations
How Dangerous Is Differentiation syndrome From CYTARABINE?
Of the 33 reports, 4 (12.1%) resulted in death, 23 (69.7%) required hospitalization, and 3 (9.1%) were considered life-threatening.
Is Differentiation syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Differentiation syndrome?
TRETINOIN (251)
ARSENIC TRIOXIDE (180)
ENASIDENIB (102)
GILTERITINIB (80)
IVOSIDENIB (80)
AZACITIDINE (50)
HYDROXYUREA (41)
DEXAMETHASONE (38)
PREDNISONE (25)
PIPERACILLIN\TAZOBACTAM (24)
Which CYTARABINE Alternatives Have Lower Differentiation syndrome Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB