Does HYDROXYUREA Cause Differentiation syndrome? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Differentiation syndrome have been filed in association with HYDROXYUREA (Hydroxyurea). This represents 0.7% of all adverse event reports for HYDROXYUREA.
41
Reports of Differentiation syndrome with HYDROXYUREA
0.7%
of all HYDROXYUREA reports
10
Deaths
22
Hospitalizations
How Dangerous Is Differentiation syndrome From HYDROXYUREA?
Of the 41 reports, 10 (24.4%) resulted in death, 22 (53.7%) required hospitalization, and 11 (26.8%) were considered life-threatening.
Is Differentiation syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROXYUREA. However, 41 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROXYUREA Cause?
Off label use (519)
Anaemia (358)
Drug ineffective (356)
Fatigue (291)
Thrombocytopenia (253)
Nausea (247)
Pyrexia (243)
Diarrhoea (222)
Febrile neutropenia (202)
Intentional product use issue (201)
What Other Drugs Cause Differentiation syndrome?
TRETINOIN (251)
ARSENIC TRIOXIDE (180)
ENASIDENIB (102)
GILTERITINIB (80)
IVOSIDENIB (80)
AZACITIDINE (50)
DEXAMETHASONE (38)
CYTARABINE (33)
PREDNISONE (25)
PIPERACILLIN\TAZOBACTAM (24)
Which HYDROXYUREA Alternatives Have Lower Differentiation syndrome Risk?
HYDROXYUREA vs HYDROXYZINE
HYDROXYUREA vs HYDROXYZINE\HYDROXYZINE
HYDROXYUREA vs HYOSCYAMINE
HYDROXYUREA vs HYPROMELLOSE 2910
HYDROXYUREA vs IBALIZUMAB-UIYK