Does DABRAFENIB Cause Adrenal insufficiency? 28 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 28 reports of Adrenal insufficiency have been filed in association with DABRAFENIB (Tafinlar). This represents 0.2% of all adverse event reports for DABRAFENIB.
28
Reports of Adrenal insufficiency with DABRAFENIB
0.2%
of all DABRAFENIB reports
4
Deaths
19
Hospitalizations
How Dangerous Is Adrenal insufficiency From DABRAFENIB?
Of the 28 reports, 4 (14.3%) resulted in death, 19 (67.9%) required hospitalization, and 3 (10.7%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DABRAFENIB. However, 28 reports have been filed with the FAERS database.
What Other Side Effects Does DABRAFENIB Cause?
Pyrexia (3,788)
Death (2,740)
Malignant neoplasm progression (1,667)
Fatigue (1,328)
Nausea (1,300)
Chills (1,235)
Rash (1,078)
Vomiting (907)
Diarrhoea (901)
Headache (697)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which DABRAFENIB Alternatives Have Lower Adrenal insufficiency Risk?
DABRAFENIB vs DABRAFENIB\TRAMETINIB
DABRAFENIB vs DACARBAZINE
DABRAFENIB vs DACLATASVIR
DABRAFENIB vs DACLIZUMAB
DABRAFENIB vs DACOMITINIB