Does DACARBAZINE Cause Cholestasis? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Cholestasis have been filed in association with DACARBAZINE (Dacarbazine). This represents 0.3% of all adverse event reports for DACARBAZINE.
15
Reports of Cholestasis with DACARBAZINE
0.3%
of all DACARBAZINE reports
7
Deaths
14
Hospitalizations
How Dangerous Is Cholestasis From DACARBAZINE?
Of the 15 reports, 7 (46.7%) resulted in death, 14 (93.3%) required hospitalization, and 6 (40.0%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DACARBAZINE. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does DACARBAZINE Cause?
Febrile neutropenia (501)
Off label use (471)
Neutropenia (400)
Drug ineffective (261)
Pyrexia (245)
Neuropathy peripheral (239)
Product use in unapproved indication (219)
Disease progression (204)
Nausea (203)
Anaemia (186)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which DACARBAZINE Alternatives Have Lower Cholestasis Risk?
DACARBAZINE vs DACLATASVIR
DACARBAZINE vs DACLIZUMAB
DACARBAZINE vs DACOMITINIB
DACARBAZINE vs DACTINOMYCIN
DACARBAZINE vs DALBAVANCIN