Does DAPTOMYCIN Cause Cholestasis? 141 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 141 reports of Cholestasis have been filed in association with DAPTOMYCIN (daptomycin). This represents 1.6% of all adverse event reports for DAPTOMYCIN.
141
Reports of Cholestasis with DAPTOMYCIN
1.6%
of all DAPTOMYCIN reports
6
Deaths
78
Hospitalizations
How Dangerous Is Cholestasis From DAPTOMYCIN?
Of the 141 reports, 6 (4.3%) resulted in death, 78 (55.3%) required hospitalization, and 3 (2.1%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DAPTOMYCIN. However, 141 reports have been filed with the FAERS database.
What Other Side Effects Does DAPTOMYCIN Cause?
Off label use (791)
Drug ineffective (658)
Product use in unapproved indication (654)
Eosinophilic pneumonia (575)
Acute kidney injury (501)
Blood creatine phosphokinase increased (461)
Pyrexia (447)
Eosinophilia (405)
Rhabdomyolysis (383)
Drug reaction with eosinophilia and systemic symptoms (307)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which DAPTOMYCIN Alternatives Have Lower Cholestasis Risk?
DAPTOMYCIN vs DARATUMUMAB
DAPTOMYCIN vs DARATUMUMAB\HYALURONIDASE-FIHJ
DAPTOMYCIN vs DARBEPOETIN ALFA
DAPTOMYCIN vs DARIDOREXANT
DAPTOMYCIN vs DARIFENACIN HYDROBROMIDE