Does DARATUMUMAB Cause Bone marrow failure? 101 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 101 reports of Bone marrow failure have been filed in association with DARATUMUMAB (DARZALEX). This represents 0.4% of all adverse event reports for DARATUMUMAB.
101
Reports of Bone marrow failure with DARATUMUMAB
0.4%
of all DARATUMUMAB reports
23
Deaths
35
Hospitalizations
How Dangerous Is Bone marrow failure From DARATUMUMAB?
Of the 101 reports, 23 (22.8%) resulted in death, 35 (34.7%) required hospitalization, and 17 (16.8%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DARATUMUMAB. However, 101 reports have been filed with the FAERS database.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which DARATUMUMAB Alternatives Have Lower Bone marrow failure Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE