Does DARATUMUMAB Cause Constipation? 317 Reports in FDA Database

Q: Does DARATUMUMAB cause Constipation?

317 reports of Constipation have been filed with the FDA for DARATUMUMAB, representing 1.2% of all DARATUMUMAB adverse event reports.

Q: How dangerous is Constipation from DARATUMUMAB?

Of 317 reports, 43 (13.6%) resulted in death and 140 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 317 reports of Constipation have been filed in association with DARATUMUMAB (DARZALEX). This represents 1.2% of all adverse event reports for DARATUMUMAB.

317

Reports of Constipation with DARATUMUMAB

1.2%

of all DARATUMUMAB reports

Deaths

140

Hospitalizations

How Dangerous Is Constipation From DARATUMUMAB?

Of the 317 reports, 43 (13.6%) resulted in death, 140 (44.2%) required hospitalization, and 17 (5.4%) were considered life-threatening.

Is Constipation Listed in the Official Label?

Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for DARATUMUMAB.

What Other Side Effects Does DARATUMUMAB Cause?

Plasma cell myeloma (2,980) Infusion related reaction (2,557) Off label use (2,494) Pneumonia (1,450) Neutropenia (1,351) Drug ineffective (1,110) Thrombocytopenia (1,089) Death (1,088) Pyrexia (1,032) Dyspnoea (996)

What Other Drugs Cause Constipation?

LENALIDOMIDE (9,635) NIRAPARIB (4,128) ADALIMUMAB (4,063) SEMAGLUTIDE (4,036) TIRZEPATIDE (3,417) ERENUMAB-AOOE (3,104) MORPHINE (2,979) OXYCODONE (2,747) PALBOCICLIB (2,705) POMALIDOMIDE (2,374)

Which DARATUMUMAB Alternatives Have Lower Constipation Risk?

DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ DARATUMUMAB vs DARBEPOETIN ALFA DARATUMUMAB vs DARIDOREXANT DARATUMUMAB vs DARIFENACIN HYDROBROMIDE DARATUMUMAB vs DAROLUTAMIDE

DARATUMUMAB Full Profile All Constipation Reports All Drugs Causing Constipation DARATUMUMAB Demographics