Does DECITABINE Cause Bone marrow failure? 111 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 111 reports of Bone marrow failure have been filed in association with DECITABINE (Decitabine). This represents 3.7% of all adverse event reports for DECITABINE.
111
Reports of Bone marrow failure with DECITABINE
3.7%
of all DECITABINE reports
18
Deaths
11
Hospitalizations
How Dangerous Is Bone marrow failure From DECITABINE?
Of the 111 reports, 18 (16.2%) resulted in death, 11 (9.9%) required hospitalization, and 12 (10.8%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DECITABINE. However, 111 reports have been filed with the FAERS database.
What Other Side Effects Does DECITABINE Cause?
Febrile neutropenia (336)
Off label use (292)
Drug ineffective (253)
Pneumonia (243)
Myelosuppression (233)
Product use in unapproved indication (195)
Neutropenia (193)
Sepsis (175)
Acute myeloid leukaemia (172)
Thrombocytopenia (170)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which DECITABINE Alternatives Have Lower Bone marrow failure Risk?
DECITABINE vs DEFERASIROX
DECITABINE vs DEFERIPRONE
DECITABINE vs DEFEROXAMINE
DECITABINE vs DEFIBROTIDE
DECITABINE vs DEFLAZACORT