Does DEFERASIROX Cause Bone marrow failure? 50 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 50 reports of Bone marrow failure have been filed in association with DEFERASIROX (Deferasirox). This represents 0.4% of all adverse event reports for DEFERASIROX.
50
Reports of Bone marrow failure with DEFERASIROX
0.4%
of all DEFERASIROX reports
15
Deaths
27
Hospitalizations
How Dangerous Is Bone marrow failure From DEFERASIROX?
Of the 50 reports, 15 (30.0%) resulted in death, 27 (54.0%) required hospitalization, and 6 (12.0%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFERASIROX. However, 50 reports have been filed with the FAERS database.
What Other Side Effects Does DEFERASIROX Cause?
Death (1,583)
Diarrhoea (993)
Serum ferritin increased (732)
Haemoglobin decreased (615)
Pyrexia (607)
Malaise (605)
Nausea (603)
Sickle cell anaemia with crisis (570)
Vomiting (520)
Pneumonia (494)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which DEFERASIROX Alternatives Have Lower Bone marrow failure Risk?
DEFERASIROX vs DEFERIPRONE
DEFERASIROX vs DEFEROXAMINE
DEFERASIROX vs DEFIBROTIDE
DEFERASIROX vs DEFLAZACORT
DEFERASIROX vs DEGARELIX