Does DEFERASIROX Cause Fibrosis? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Fibrosis have been filed in association with DEFERASIROX (Deferasirox). This represents 0.1% of all adverse event reports for DEFERASIROX.
8
Reports of Fibrosis with DEFERASIROX
0.1%
of all DEFERASIROX reports
1
Deaths
3
Hospitalizations
How Dangerous Is Fibrosis From DEFERASIROX?
Of the 8 reports, 1 (12.5%) resulted in death, 3 (37.5%) required hospitalization, and 1 (12.5%) were considered life-threatening.
Is Fibrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFERASIROX. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does DEFERASIROX Cause?
Death (1,583)
Diarrhoea (993)
Serum ferritin increased (732)
Haemoglobin decreased (615)
Pyrexia (607)
Malaise (605)
Nausea (603)
Sickle cell anaemia with crisis (570)
Vomiting (520)
Pneumonia (494)
What Other Drugs Cause Fibrosis?
METHOTREXATE (122)
ADALIMUMAB (118)
PREDNISONE (85)
RITUXIMAB (84)
MYCOPHENOLATE MOFETIL (70)
DICLOFENAC (67)
METFORMIN (52)
HYDROXYCHLOROQUINE (51)
TACROLIMUS (51)
ETANERCEPT (50)
Which DEFERASIROX Alternatives Have Lower Fibrosis Risk?
DEFERASIROX vs DEFERIPRONE
DEFERASIROX vs DEFEROXAMINE
DEFERASIROX vs DEFIBROTIDE
DEFERASIROX vs DEFLAZACORT
DEFERASIROX vs DEGARELIX