Does METHOTREXATE Cause Fibrosis? 122 Reports in FDA Database
Grow Your Own Natural Pharmacy at Home
Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.
According to the FDA Adverse Event Reporting System (FAERS), 122 reports of Fibrosis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
122
Reports of Fibrosis with METHOTREXATE
0.1%
of all METHOTREXATE reports
3
Deaths
37
Hospitalizations
How Dangerous Is Fibrosis From METHOTREXATE?
Of the 122 reports, 3 (2.5%) resulted in death, 37 (30.3%) required hospitalization, and 12 (9.8%) were considered life-threatening.
Is Fibrosis Listed in the Official Label?
Yes, Fibrosis is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Fibrosis?
ADALIMUMAB (118)
PREDNISONE (85)
RITUXIMAB (84)
MYCOPHENOLATE MOFETIL (70)
DICLOFENAC (67)
METFORMIN (52)
HYDROXYCHLOROQUINE (51)
TACROLIMUS (51)
ETANERCEPT (50)
RUXOLITINIB (47)
Which METHOTREXATE Alternatives Have Lower Fibrosis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA