Fibrosis: Which Medications Cause It? (1,849 Reports Across 216 Drugs)
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Fibrosis has been reported as an adverse event with 216 different drugs in the FDA's FAERS database, with 1,849 total reports. 165 of these reports resulted in death.The drugs most commonly associated with Fibrosis are METHOTREXATE, ADALIMUMAB, and PREDNISONE.
1,849
Total Reports
216
Drugs Involved
165
Deaths
714
Hospitalizations
54.4 yrs
Average Patient Age
58.9% / 41.1%
Female / Male
Which Drugs Cause Fibrosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 122 | 0.1% | 3 | 37 | 12 |
| ADALIMUMAB | 118 | 0.0% | 3 | 50 | 1 |
| PREDNISONE | 85 | 0.1% | 6 | 54 | 2 |
| RITUXIMAB | 84 | 0.1% | 5 | 58 | 4 |
| MYCOPHENOLATE MOFETIL | 70 | 0.1% | 5 | 46 | 3 |
| DICLOFENAC | 67 | 0.1% | 0 | 22 | 0 |
| METFORMIN | 52 | 0.1% | 0 | 1 | 0 |
| HYDROXYCHLOROQUINE | 51 | 0.1% | 1 | 38 | 2 |
| TACROLIMUS | 51 | 0.1% | 6 | 24 | 2 |
| ETANERCEPT | 50 | 0.0% | 4 | 9 | 1 |
| RUXOLITINIB | 47 | 0.1% | 5 | 10 | 0 |
| ATENOLOL | 46 | 0.4% | 0 | 3 | 0 |
| TOCILIZUMAB | 46 | 0.1% | 4 | 15 | 6 |
| ATORVASTATIN | 44 | 0.1% | 0 | 2 | 0 |
| CYCLOPHOSPHAMIDE | 43 | 0.0% | 4 | 26 | 1 |
| VANCOMYCIN | 43 | 0.1% | 0 | 43 | 0 |
| PIRFENIDONE | 42 | 0.1% | 12 | 23 | 0 |
| CISPLATIN | 37 | 0.1% | 2 | 26 | 0 |
| FUROSEMIDE | 37 | 0.1% | 0 | 36 | 1 |
| ROSUVASTATIN | 37 | 0.1% | 0 | 33 | 0 |