DEFERIPRONE for Off label use: Side Effects & Safety Data
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There are 283 adverse event reports in the FDA FAERS database where DEFERIPRONE was used for Off label use.
Most Reported Side Effects for DEFERIPRONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 916 | 36.8% | 91 | 304 |
| Death | 190 | 7.6% | 190 | 27 |
| Sickle cell anaemia with crisis | 167 | 6.7% | 1 | 156 |
| Nausea | 135 | 5.4% | 3 | 20 |
| Agranulocytosis | 126 | 5.1% | 8 | 68 |
| Vomiting | 111 | 4.5% | 3 | 24 |
| Ill-defined disorder | 106 | 4.3% | 9 | 100 |
| Fatigue | 99 | 4.0% | 1 | 22 |
| Neutropenia | 97 | 3.9% | 3 | 26 |
| Pyrexia | 87 | 3.5% | 7 | 53 |
| Abdominal discomfort | 83 | 3.3% | 1 | 11 |
| Prescribed overdose | 83 | 3.3% | 4 | 27 |
| Arthralgia | 76 | 3.1% | 4 | 23 |
| Diarrhoea | 76 | 3.1% | 2 | 26 |
| Haemoglobin decreased | 73 | 2.9% | 1 | 45 |
Other Indications for DEFERIPRONE
Haemochromatosis (1,537)
Transfusion (745)
Sickle cell disease (574)
Red blood cell transfusion (442)
Thalassaemia beta (389)
Thalassaemia (331)
Iron overload (164)
Myelodysplastic syndrome (162)
Sickle cell anaemia (125)
Iron metabolism disorder (78)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)