Does DEFERIPRONE Cause Agranulocytosis? 126 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 126 reports of Agranulocytosis have been filed in association with DEFERIPRONE (FERRIPROX). This represents 5.1% of all adverse event reports for DEFERIPRONE.
126
Reports of Agranulocytosis with DEFERIPRONE
5.1%
of all DEFERIPRONE reports
8
Deaths
68
Hospitalizations
How Dangerous Is Agranulocytosis From DEFERIPRONE?
Of the 126 reports, 8 (6.3%) resulted in death, 68 (54.0%) required hospitalization, and 24 (19.0%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for DEFERIPRONE.
What Other Side Effects Does DEFERIPRONE Cause?
Off label use (916)
Death (190)
Sickle cell anaemia with crisis (167)
Nausea (135)
Vomiting (111)
Ill-defined disorder (106)
Fatigue (99)
Neutropenia (97)
Pyrexia (87)
Abdominal discomfort (83)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which DEFERIPRONE Alternatives Have Lower Agranulocytosis Risk?
DEFERIPRONE vs DEFEROXAMINE
DEFERIPRONE vs DEFIBROTIDE
DEFERIPRONE vs DEFLAZACORT
DEFERIPRONE vs DEGARELIX
DEFERIPRONE vs DELAFLOXACIN MEGLUMINE