Does DEFERIPRONE Cause Nephrolithiasis? 30 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 30 reports of Nephrolithiasis have been filed in association with DEFERIPRONE (FERRIPROX). This represents 1.2% of all adverse event reports for DEFERIPRONE.
30
Reports of Nephrolithiasis with DEFERIPRONE
1.2%
of all DEFERIPRONE reports
1
Deaths
12
Hospitalizations
How Dangerous Is Nephrolithiasis From DEFERIPRONE?
Of the 30 reports, 1 (3.3%) resulted in death, 12 (40.0%) required hospitalization, and 6 (20.0%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFERIPRONE. However, 30 reports have been filed with the FAERS database.
What Other Side Effects Does DEFERIPRONE Cause?
Off label use (916)
Death (190)
Sickle cell anaemia with crisis (167)
Nausea (135)
Agranulocytosis (126)
Vomiting (111)
Ill-defined disorder (106)
Fatigue (99)
Neutropenia (97)
Pyrexia (87)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which DEFERIPRONE Alternatives Have Lower Nephrolithiasis Risk?
DEFERIPRONE vs DEFEROXAMINE
DEFERIPRONE vs DEFIBROTIDE
DEFERIPRONE vs DEFLAZACORT
DEFERIPRONE vs DEGARELIX
DEFERIPRONE vs DELAFLOXACIN MEGLUMINE