Does DEFIBROTIDE Cause Bone marrow failure? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Bone marrow failure have been filed in association with DEFIBROTIDE (DEFITELIO). This represents 0.5% of all adverse event reports for DEFIBROTIDE.
17
Reports of Bone marrow failure with DEFIBROTIDE
0.5%
of all DEFIBROTIDE reports
4
Deaths
3
Hospitalizations
How Dangerous Is Bone marrow failure From DEFIBROTIDE?
Of the 17 reports, 4 (23.5%) resulted in death, 3 (17.6%) required hospitalization.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFIBROTIDE. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does DEFIBROTIDE Cause?
Off label use (1,323)
Venoocclusive disease (576)
Death (463)
Multiple organ dysfunction syndrome (372)
Venoocclusive liver disease (355)
Intentional product use issue (201)
Hypotension (169)
Haemorrhage (156)
Sepsis (143)
Acute graft versus host disease (140)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which DEFIBROTIDE Alternatives Have Lower Bone marrow failure Risk?
DEFIBROTIDE vs DEFLAZACORT
DEFIBROTIDE vs DEGARELIX
DEFIBROTIDE vs DELAFLOXACIN MEGLUMINE
DEFIBROTIDE vs DELAMANID
DEFIBROTIDE vs DELANDISTROGENE MOXEPARVOVEC-ROKL