Does DENOSUMAB Cause Intervertebral disc degeneration? 104 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 104 reports of Intervertebral disc degeneration have been filed in association with DENOSUMAB (Bilprevda). This represents 0.1% of all adverse event reports for DENOSUMAB.
104
Reports of Intervertebral disc degeneration with DENOSUMAB
0.1%
of all DENOSUMAB reports
7
Deaths
13
Hospitalizations
How Dangerous Is Intervertebral disc degeneration From DENOSUMAB?
Of the 104 reports, 7 (6.7%) resulted in death, 13 (12.5%) required hospitalization, and 1 (1.0%) were considered life-threatening.
Is Intervertebral disc degeneration Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DENOSUMAB. However, 104 reports have been filed with the FAERS database.
What Other Side Effects Does DENOSUMAB Cause?
Off label use (34,612)
Death (16,545)
Osteonecrosis of jaw (8,438)
Arthralgia (5,890)
Pain in extremity (4,541)
Back pain (4,465)
Pain (4,102)
Product storage error (3,621)
Fall (3,322)
Fatigue (3,009)
What Other Drugs Cause Intervertebral disc degeneration?
ADALIMUMAB (873)
ALENDRONATE (339)
ETANERCEPT (311)
METHOTREXATE (308)
EMTRICITABINE\TENOFOVIR DISOPROXIL (210)
PREGABALIN (204)
PREDNISONE (202)
RITUXIMAB (200)
OXYCODONE (184)
SODIUM OXYBATE (178)
Which DENOSUMAB Alternatives Have Lower Intervertebral disc degeneration Risk?
DENOSUMAB vs DEOXYCHOLIC ACID
DENOSUMAB vs DEPAKINE CHRONO
DENOSUMAB vs DEPAKOTE
DENOSUMAB vs DEPO-PROVERA
DENOSUMAB vs DERMATOPHAGOIDES FARINAE