Intervertebral disc degeneration: Which Medications Cause It? (6,089 Reports Across 326 Drugs)
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Intervertebral disc degeneration has been reported as an adverse event with 326 different drugs in the FDA's FAERS database, with 6,089 total reports. 197 of these reports resulted in death.The drugs most commonly associated with Intervertebral disc degeneration are ADALIMUMAB, ALENDRONATE, and ETANERCEPT.
6,089
Total Reports
326
Drugs Involved
197
Deaths
2,274
Hospitalizations
58.9 yrs
Average Patient Age
66.9% / 33.1%
Female / Male
Which Drugs Cause Intervertebral disc degeneration Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADALIMUMAB | 873 | 0.2% | 3 | 332 | 4 |
| ALENDRONATE | 339 | 1.2% | 12 | 321 | 37 |
| ETANERCEPT | 311 | 0.1% | 0 | 65 | 4 |
| METHOTREXATE | 308 | 0.1% | 0 | 92 | 1 |
| EMTRICITABINE\TENOFOVIR DISOPROXIL | 210 | 0.5% | 3 | 19 | 0 |
| PREGABALIN | 204 | 0.2% | 0 | 41 | 8 |
| PREDNISONE | 202 | 0.1% | 1 | 119 | 56 |
| RITUXIMAB | 200 | 0.1% | 4 | 69 | 0 |
| OXYCODONE | 184 | 0.1% | 21 | 57 | 10 |
| SODIUM OXYBATE | 178 | 0.3% | 0 | 34 | 1 |
| GABAPENTIN | 147 | 0.2% | 2 | 96 | 54 |
| TOFACITINIB | 147 | 0.1% | 0 | 22 | 1 |
| SECUKINUMAB | 144 | 0.1% | 2 | 20 | 6 |
| EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL | 142 | 0.8% | 2 | 7 | 0 |
| UPADACITINIB | 142 | 0.2% | 0 | 57 | 0 |
| LEFLUNOMIDE | 138 | 0.2% | 0 | 25 | 1 |
| ALENDRONATE\CHOLECALCIFEROL | 132 | 5.1% | 0 | 124 | 42 |
| ALBUTEROL | 130 | 0.1% | 0 | 108 | 55 |
| PANTOPRAZOLE | 124 | 0.2% | 1 | 90 | 61 |
| TOCILIZUMAB | 120 | 0.1% | 1 | 45 | 0 |