Does TOFACITINIB Cause Intervertebral disc degeneration? 147 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 147 reports of Intervertebral disc degeneration have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.1% of all adverse event reports for TOFACITINIB.
147
Reports of Intervertebral disc degeneration with TOFACITINIB
0.1%
of all TOFACITINIB reports
0
Deaths
22
Hospitalizations
How Dangerous Is Intervertebral disc degeneration From TOFACITINIB?
Of the 147 reports, 22 (15.0%) required hospitalization, and 1 (0.7%) were considered life-threatening.
Is Intervertebral disc degeneration Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 147 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Intervertebral disc degeneration?
ADALIMUMAB (873)
ALENDRONATE (339)
ETANERCEPT (311)
METHOTREXATE (308)
EMTRICITABINE\TENOFOVIR DISOPROXIL (210)
PREGABALIN (204)
PREDNISONE (202)
RITUXIMAB (200)
OXYCODONE (184)
SODIUM OXYBATE (178)
Which TOFACITINIB Alternatives Have Lower Intervertebral disc degeneration Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN