Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does METHOTREXATE Cause Intervertebral disc degeneration? 308 Reports in FDA Database

Grow Your Own Natural Pharmacy at Home

Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.

Get the Kit

According to the FDA Adverse Event Reporting System (FAERS), 308 reports of Intervertebral disc degeneration have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.

308
Reports of Intervertebral disc degeneration with METHOTREXATE
0.1%
of all METHOTREXATE reports
0
Deaths
92
Hospitalizations

How Dangerous Is Intervertebral disc degeneration From METHOTREXATE?

Of the 308 reports, 92 (29.9%) required hospitalization, and 1 (0.3%) were considered life-threatening.

Is Intervertebral disc degeneration Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 308 reports have been filed with the FAERS database.

What Other Side Effects Does METHOTREXATE Cause?

Drug ineffective (70,142) Rheumatoid arthritis (29,254) Off label use (24,020) Pain (23,773) Drug intolerance (22,555) Arthralgia (21,831) Fatigue (19,885) Nausea (18,715) Joint swelling (17,657) Drug hypersensitivity (16,677)

What Other Drugs Cause Intervertebral disc degeneration?

ADALIMUMAB (873) ALENDRONATE (339) ETANERCEPT (311) EMTRICITABINE\TENOFOVIR DISOPROXIL (210) PREGABALIN (204) PREDNISONE (202) RITUXIMAB (200) OXYCODONE (184) SODIUM OXYBATE (178) GABAPENTIN (147)

Which METHOTREXATE Alternatives Have Lower Intervertebral disc degeneration Risk?

METHOTREXATE vs METHOXSALEN METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA METHOTREXATE vs METHYL ALCOHOL METHOTREXATE vs METHYLCOBALAMIN METHOTREXATE vs METHYLDOPA

Related Pages

METHOTREXATE Full Profile All Intervertebral disc degeneration Reports All Drugs Causing Intervertebral disc degeneration METHOTREXATE Demographics