Does DEXAMETHASONE Cause Osteonecrosis? 531 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 531 reports of Osteonecrosis have been filed in association with DEXAMETHASONE (Dexamethasone Sodium Phosphate). This represents 0.4% of all adverse event reports for DEXAMETHASONE.
531
Reports of Osteonecrosis with DEXAMETHASONE
0.4%
of all DEXAMETHASONE reports
26
Deaths
137
Hospitalizations
How Dangerous Is Osteonecrosis From DEXAMETHASONE?
Of the 531 reports, 26 (4.9%) resulted in death, 137 (25.8%) required hospitalization, and 16 (3.0%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEXAMETHASONE. However, 531 reports have been filed with the FAERS database.
What Other Side Effects Does DEXAMETHASONE Cause?
Off label use (13,439)
Plasma cell myeloma (9,207)
Drug ineffective (8,359)
Pneumonia (6,073)
Neutropenia (6,050)
Thrombocytopenia (5,873)
Diarrhoea (4,816)
Pyrexia (4,639)
Disease progression (4,545)
Febrile neutropenia (4,382)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
ZOLEDRONIC ACID (511)
Which DEXAMETHASONE Alternatives Have Lower Osteonecrosis Risk?
DEXAMETHASONE vs DEXAMETHASONE\DEXAMETHASONE
DEXAMETHASONE vs DEXAMETHASONE\NEOMYCIN
DEXAMETHASONE vs DEXAMETHASONE\NEOMYCIN\POLYMYXIN B
DEXAMETHASONE vs DEXAMETHASONE\TOBRAMYCIN
DEXAMETHASONE vs DEXCHLORPHENIRAMINE