Does DEXRAZOXANE Cause Bone marrow failure? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Bone marrow failure have been filed in association with DEXRAZOXANE (Dexrazoxane). This represents 4.9% of all adverse event reports for DEXRAZOXANE.
55
Reports of Bone marrow failure with DEXRAZOXANE
4.9%
of all DEXRAZOXANE reports
4
Deaths
25
Hospitalizations
How Dangerous Is Bone marrow failure From DEXRAZOXANE?
Of the 55 reports, 4 (7.3%) resulted in death, 25 (45.5%) required hospitalization, and 19 (34.5%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEXRAZOXANE. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does DEXRAZOXANE Cause?
Febrile neutropenia (315)
Off label use (266)
Clostridium difficile colitis (91)
Cellulitis (84)
Product use in unapproved indication (84)
Pyrexia (81)
Fungal infection (74)
Bacterial infection (73)
Lymphoid tissue hypoplasia (72)
Lymphopenia (70)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which DEXRAZOXANE Alternatives Have Lower Bone marrow failure Risk?
DEXRAZOXANE vs DEXTRAN 70\HYPROMELLOSE 2910
DEXRAZOXANE vs DEXTROAMPHETAMINE
DEXRAZOXANE vs DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE AND AMPHETAMINE
DEXRAZOXANE vs DEXTROMETHORPHAN
DEXRAZOXANE vs DEXTROMETHORPHAN HYDROBROMIDE