DIPHENHYDRAMINE for Prophylaxis: Side Effects & Safety Data

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There are 160 adverse event reports in the FDA FAERS database where DIPHENHYDRAMINE was used for Prophylaxis.

Most Reported Side Effects for DIPHENHYDRAMINE

Side Effect	Reports	%	Deaths	Hosp.
Toxicity to various agents	4,596	17.8%	3,875	1,338
Drug ineffective	3,511	13.6%	380	1,157
Completed suicide	3,081	11.9%	3,073	1,053
Off label use	2,639	10.2%	388	1,029
Fatigue	2,605	10.1%	542	917
Drug abuse	2,602	10.1%	2,204	237
Headache	2,171	8.4%	515	950
Overdose	2,082	8.1%	709	722
Pain	2,080	8.1%	484	850
Nausea	1,905	7.4%	320	1,080
Infusion related reaction	1,827	7.1%	510	726
Drug hypersensitivity	1,791	6.9%	331	509
Somnolence	1,612	6.2%	66	419
Rheumatoid arthritis	1,463	5.7%	456	570
Hypersensitivity	1,392	5.4%	474	390