Does DIPHENHYDRAMINE Cause Pruritus? 1,039 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,039 reports of Pruritus have been filed in association with DIPHENHYDRAMINE (Allergy Relief). This represents 4.0% of all adverse event reports for DIPHENHYDRAMINE.
1,039
Reports of Pruritus with DIPHENHYDRAMINE
4.0%
of all DIPHENHYDRAMINE reports
263
Deaths
405
Hospitalizations
How Dangerous Is Pruritus From DIPHENHYDRAMINE?
Of the 1,039 reports, 263 (25.3%) resulted in death, 405 (39.0%) required hospitalization, and 218 (21.0%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DIPHENHYDRAMINE. However, 1,039 reports have been filed with the FAERS database.
What Other Side Effects Does DIPHENHYDRAMINE Cause?
Toxicity to various agents (4,596)
Drug ineffective (3,511)
Completed suicide (3,081)
Off label use (2,639)
Fatigue (2,605)
Drug abuse (2,602)
Headache (2,171)
Overdose (2,082)
Pain (2,080)
Nausea (1,905)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which DIPHENHYDRAMINE Alternatives Have Lower Pruritus Risk?
DIPHENHYDRAMINE vs DIPHENHYDRAMINE UNKNOWN PRODUCT
DIPHENHYDRAMINE vs DIPHENHYDRAMINE\IBUPROFEN
DIPHENHYDRAMINE vs DIPHENHYDRAMINE\NAPROXEN
DIPHENHYDRAMINE vs DIPHENOXYLATE
DIPHENHYDRAMINE vs DIPHTHERIA AND TETANUS TOXOIDS AND ACELLULAR PERTUSSIS ADSORBED AND INACTIVATED POLIOVIRUS VACCINE