Does DIVALPROEX Cause Cholestasis? 38 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 38 reports of Cholestasis have been filed in association with DIVALPROEX (Divalproex Sodium). This represents 0.3% of all adverse event reports for DIVALPROEX.
38
Reports of Cholestasis with DIVALPROEX
0.3%
of all DIVALPROEX reports
3
Deaths
18
Hospitalizations
How Dangerous Is Cholestasis From DIVALPROEX?
Of the 38 reports, 3 (7.9%) resulted in death, 18 (47.4%) required hospitalization, and 1 (2.6%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DIVALPROEX. However, 38 reports have been filed with the FAERS database.
What Other Side Effects Does DIVALPROEX Cause?
Drug ineffective (1,121)
Seizure (1,095)
Off label use (576)
Somnolence (545)
Drug interaction (540)
Nausea (526)
Weight increased (509)
Tremor (461)
Toxicity to various agents (452)
Vomiting (436)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which DIVALPROEX Alternatives Have Lower Cholestasis Risk?
DIVALPROEX vs DOBUTAMINE
DIVALPROEX vs DOBUTAMINE\DOBUTAMINE
DIVALPROEX vs DOCETAXEL
DIVALPROEX vs DOCETAXEL ANHYDROUS
DIVALPROEX vs DOCETAXEL\DOCETAXEL ANHYDROUS