Does DIVALPROEX Cause Macrocephaly? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Macrocephaly have been filed in association with DIVALPROEX (Divalproex Sodium). This represents 0.1% of all adverse event reports for DIVALPROEX.
6
Reports of Macrocephaly with DIVALPROEX
0.1%
of all DIVALPROEX reports
1
Deaths
0
Hospitalizations
How Dangerous Is Macrocephaly From DIVALPROEX?
Of the 6 reports, 1 (16.7%) resulted in death, and 1 (16.7%) were considered life-threatening.
Is Macrocephaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DIVALPROEX. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does DIVALPROEX Cause?
Drug ineffective (1,121)
Seizure (1,095)
Off label use (576)
Somnolence (545)
Drug interaction (540)
Nausea (526)
Weight increased (509)
Tremor (461)
Toxicity to various agents (452)
Vomiting (436)
What Other Drugs Cause Macrocephaly?
LAMIVUDINE\ZIDOVUDINE (40)
NEVIRAPINE (37)
LAMIVUDINE (34)
DICLOFENAC (33)
IBUPROFEN (29)
LEVOTHYROXINE (26)
ACETAMINOPHEN (25)
LYNESTRENOL (25)
OMEPRAZOLE (25)
VALPROATE (23)
Which DIVALPROEX Alternatives Have Lower Macrocephaly Risk?
DIVALPROEX vs DOBUTAMINE
DIVALPROEX vs DOBUTAMINE\DOBUTAMINE
DIVALPROEX vs DOCETAXEL
DIVALPROEX vs DOCETAXEL ANHYDROUS
DIVALPROEX vs DOCETAXEL\DOCETAXEL ANHYDROUS