Does DOLUTEGRAVIR Cause Progressive multifocal leukoencephalopathy? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Progressive multifocal leukoencephalopathy have been filed in association with DOLUTEGRAVIR (Juluca). This represents 0.3% of all adverse event reports for DOLUTEGRAVIR.
33
Reports of Progressive multifocal leukoencephalopathy with DOLUTEGRAVIR
0.3%
of all DOLUTEGRAVIR reports
13
Deaths
8
Hospitalizations
How Dangerous Is Progressive multifocal leukoencephalopathy From DOLUTEGRAVIR?
Of the 33 reports, 13 (39.4%) resulted in death, 8 (24.2%) required hospitalization, and 1 (3.0%) were considered life-threatening.
Is Progressive multifocal leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DOLUTEGRAVIR. However, 33 reports have been filed with the FAERS database.
What Other Side Effects Does DOLUTEGRAVIR Cause?
Foetal exposure during pregnancy (1,036)
Exposure during pregnancy (776)
Virologic failure (770)
Pathogen resistance (586)
Maternal exposure during pregnancy (517)
Viral mutation identified (510)
Treatment failure (453)
Drug ineffective (447)
Off label use (413)
Blood hiv rna increased (410)
What Other Drugs Cause Progressive multifocal leukoencephalopathy?
NATALIZUMAB (1,668)
RITUXIMAB (1,647)
CYCLOPHOSPHAMIDE (782)
PREDNISONE (606)
PREDNISOLONE (439)
TACROLIMUS (438)
METHOTREXATE (428)
DOXORUBICIN (421)
MYCOPHENOLATE MOFETIL (414)
VINCRISTINE (376)
Which DOLUTEGRAVIR Alternatives Have Lower Progressive multifocal leukoencephalopathy Risk?
DOLUTEGRAVIR vs DOLUTEGRAVIR\LAMIVUDINE
DOLUTEGRAVIR vs DOLUTEGRAVIR\LAMIVUDINE\TENOFOVIR DISOPROXIL
DOLUTEGRAVIR vs DOLUTEGRAVIR\RILPIVIRINE
DOLUTEGRAVIR vs DOMPERIDONE
DOLUTEGRAVIR vs DOMPERIDONE\PANTOPRAZOLE