DORNASE ALFA for Infective pulmonary exacerbation of cystic fibrosis: Side Effects & Safety Data
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There are 78 adverse event reports in the FDA FAERS database where DORNASE ALFA was used for Infective pulmonary exacerbation of cystic fibrosis.
Most Reported Side Effects for DORNASE ALFA
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| No adverse event | 889 | 16.4% | 1 | 3 |
| Cystic fibrosis | 565 | 10.4% | 7 | 471 |
| Off label use | 522 | 9.6% | 23 | 94 |
| Hospitalisation | 512 | 9.4% | 3 | 432 |
| Pneumonia | 377 | 6.9% | 37 | 321 |
| Condition aggravated | 304 | 5.6% | 27 | 250 |
| Dyspnoea | 246 | 4.5% | 24 | 197 |
| Infective pulmonary exacerbation of cystic fibrosis | 245 | 4.5% | 2 | 204 |
| Product storage error | 242 | 4.5% | 0 | 1 |
| Death | 225 | 4.1% | 222 | 10 |
| Cough | 195 | 3.6% | 1 | 82 |
| Intercepted medication error | 125 | 2.3% | 0 | 1 |
| Intentional product use issue | 121 | 2.2% | 5 | 20 |
| Lung disorder | 117 | 2.2% | 2 | 95 |
| Intercepted product storage error | 115 | 2.1% | 0 | 0 |
Other Indications for DORNASE ALFA
Cystic fibrosis (2,769)
Product used for unknown indication (1,615)
Bronchiectasis (137)
Cystic fibrosis lung (79)
Lung disorder (59)
Chronic respiratory failure (36)
Chronic obstructive pulmonary disease (34)
Pneumonia (33)
Interstitial lung disease (31)
Asthma (30)
Other Drugs Used for Infective pulmonary exacerbation of cystic fibrosis
AZTREONAM LYSINE (185)
TOBRAMYCIN (144)
CIPROFLOXACIN (62)
MEROPENEM (44)
VANCOMYCIN (42)
PIPERACILLIN\TAZOBACTAM (26)
OSELTAMIVIR (24)
PANCRELIPASE AMYLASE\PANCRELIPASE LIPASE\PANCRELIPASE PROTEASE (18)
ELEXACAFTOR\IVACAFTOR\TEZACAFTOR (13)
LINEZOLID (12)