Does DORNASE ALFA Cause Intentional product use issue? 121 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 121 reports of Intentional product use issue have been filed in association with DORNASE ALFA (Pulmozyme). This represents 2.2% of all adverse event reports for DORNASE ALFA.
121
Reports of Intentional product use issue with DORNASE ALFA
2.2%
of all DORNASE ALFA reports
5
Deaths
20
Hospitalizations
How Dangerous Is Intentional product use issue From DORNASE ALFA?
Of the 121 reports, 5 (4.1%) resulted in death, 20 (16.5%) required hospitalization, and 2 (1.7%) were considered life-threatening.
Is Intentional product use issue Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 121 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Intentional product use issue?
INFLIXIMAB (11,028)
RITUXIMAB (9,602)
INFLIXIMAB-DYYB (7,549)
TOCILIZUMAB (5,078)
METHOTREXATE (4,087)
PREDNISONE (3,961)
ABATACEPT (3,693)
ADALIMUMAB (3,557)
NIVOLUMAB (3,297)
LEFLUNOMIDE (3,280)
Which DORNASE ALFA Alternatives Have Lower Intentional product use issue Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68