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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Intentional product use issue: Which Medications Cause It? (81,897 Reports Across 1,311 Drugs)

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Intentional product use issue has been reported as an adverse event with 1,311 different drugs in the FDA's FAERS database, with 81,897 total reports. 8,674 of these reports resulted in death.The drugs most commonly associated with Intentional product use issue are INFLIXIMAB, RITUXIMAB, and INFLIXIMAB-DYYB.

81,897
Total Reports
1,311
Drugs Involved
8,674
Deaths
17,894
Hospitalizations
55.1 yrs
Average Patient Age
58.0% / 42.0%
Female / Male

Which Drugs Cause Intentional product use issue Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
INFLIXIMAB 11,028 7.9% 1,280 3,261 1,489
RITUXIMAB 9,602 5.4% 2,174 3,521 1,897
INFLIXIMAB-DYYB 7,549 29.5% 125 1,938 30
TOCILIZUMAB 5,078 5.2% 1,660 2,018 1,506
METHOTREXATE 4,087 1.6% 1,486 2,095 1,736
PREDNISONE 3,961 2.5% 1,305 1,889 1,437
ABATACEPT 3,693 3.2% 1,146 1,645 1,427
ADALIMUMAB 3,557 0.7% 1,333 1,841 1,622
NIVOLUMAB 3,297 3.8% 1,461 827 143
LEFLUNOMIDE 3,280 5.8% 1,468 1,840 1,707
HYDROXYCHLOROQUINE 3,059 4.6% 1,257 1,656 1,470
SULFASALAZINE 2,940 7.3% 1,177 1,554 1,444
TOFACITINIB 2,913 1.9% 1,078 1,435 1,323
APIXABAN 2,874 1.8% 226 845 198
ETANERCEPT 2,789 0.8% 999 1,448 1,274
PREGABALIN 2,770 2.7% 353 750 393
CETIRIZINE 2,721 5.7% 1,183 1,456 1,415
DICLOFENAC 2,648 3.1% 1,354 1,514 1,507
GOLIMUMAB 2,616 3.8% 1,041 1,323 1,259
FOLIC ACID 2,551 11.2% 1,251 1,477 1,376

View all 1,311 drugs →

Top 3 Drugs Associated With Intentional product use issue

11,028 reports
9,602 reports
7,549 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)