Does DORNASE ALFA Cause Interstitial lung disease? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Interstitial lung disease have been filed in association with DORNASE ALFA (Pulmozyme). This represents 0.4% of all adverse event reports for DORNASE ALFA.
24
Reports of Interstitial lung disease with DORNASE ALFA
0.4%
of all DORNASE ALFA reports
23
Deaths
23
Hospitalizations
How Dangerous Is Interstitial lung disease From DORNASE ALFA?
Of the 24 reports, 23 (95.8%) resulted in death, 23 (95.8%) required hospitalization, and 24 (100.0%) were considered life-threatening.
Is Interstitial lung disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 24 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Interstitial lung disease?
METHOTREXATE (3,049)
RITUXIMAB (2,458)
PEMBROLIZUMAB (2,113)
PREDNISONE (1,850)
CYCLOPHOSPHAMIDE (1,725)
NIVOLUMAB (1,538)
AMIODARONE (1,421)
DOXORUBICIN (1,352)
ETANERCEPT (1,267)
ADALIMUMAB (1,250)
Which DORNASE ALFA Alternatives Have Lower Interstitial lung disease Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68