Does DORNASE ALFA Cause Pyrexia? 108 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 108 reports of Pyrexia have been filed in association with DORNASE ALFA (Pulmozyme). This represents 2.0% of all adverse event reports for DORNASE ALFA.
108
Reports of Pyrexia with DORNASE ALFA
2.0%
of all DORNASE ALFA reports
25
Deaths
78
Hospitalizations
How Dangerous Is Pyrexia From DORNASE ALFA?
Of the 108 reports, 25 (23.1%) resulted in death, 78 (72.2%) required hospitalization, and 26 (24.1%) were considered life-threatening.
Is Pyrexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 108 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Pyrexia?
ADALIMUMAB (12,160)
METHOTREXATE (10,158)
RITUXIMAB (10,061)
PREDNISONE (8,141)
ETANERCEPT (7,626)
INFLIXIMAB (6,560)
ACETAMINOPHEN (6,414)
CYCLOPHOSPHAMIDE (6,126)
TOCILIZUMAB (5,529)
LENALIDOMIDE (5,496)
Which DORNASE ALFA Alternatives Have Lower Pyrexia Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68