Does DOXYCYCLINE Cause Cholestasis? 77 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 77 reports of Cholestasis have been filed in association with DOXYCYCLINE (Doxycycline). This represents 0.4% of all adverse event reports for DOXYCYCLINE.
77
Reports of Cholestasis with DOXYCYCLINE
0.4%
of all DOXYCYCLINE reports
4
Deaths
48
Hospitalizations
How Dangerous Is Cholestasis From DOXYCYCLINE?
Of the 77 reports, 4 (5.2%) resulted in death, 48 (62.3%) required hospitalization, and 3 (3.9%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DOXYCYCLINE. However, 77 reports have been filed with the FAERS database.
What Other Side Effects Does DOXYCYCLINE Cause?
Drug ineffective (2,238)
Off label use (1,630)
Nausea (1,391)
Vomiting (1,357)
Drug hypersensitivity (1,294)
Rash (1,267)
Headache (1,061)
Condition aggravated (1,052)
Malaise (994)
Fatigue (979)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which DOXYCYCLINE Alternatives Have Lower Cholestasis Risk?
DOXYCYCLINE vs DOXYCYCLINE HYCLATE
DOXYCYCLINE vs DOXYCYCLINE\DOXYCYCLINE HYCLATE
DOXYCYCLINE vs DOXYLAMINE
DOXYCYCLINE vs DOXYLAMINE\PYRIDOXINE
DOXYCYCLINE vs DRONABINOL