DURVALUMAB for K-ras gene mutation: Side Effects & Safety Data
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There are 5 adverse event reports in the FDA FAERS database where DURVALUMAB was used for K-ras gene mutation.
Most Reported Side Effects for DURVALUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 2,817 | 16.4% | 2,816 | 98 |
| Malignant neoplasm progression | 1,330 | 7.8% | 343 | 166 |
| Pneumonitis | 827 | 4.8% | 221 | 333 |
| Radiation pneumonitis | 786 | 4.6% | 112 | 343 |
| Pyrexia | 573 | 3.3% | 79 | 372 |
| Diarrhoea | 530 | 3.1% | 99 | 267 |
| Pneumonia | 453 | 2.6% | 169 | 300 |
| Dyspnoea | 444 | 2.6% | 113 | 215 |
| Interstitial lung disease | 430 | 2.5% | 144 | 220 |
| Off label use | 395 | 2.3% | 70 | 102 |
| Fatigue | 367 | 2.1% | 57 | 102 |
| Rash | 359 | 2.1% | 43 | 94 |
| Neutrophil count decreased | 343 | 2.0% | 49 | 76 |
| Asthenia | 326 | 1.9% | 104 | 121 |
| Colitis | 319 | 1.9% | 73 | 164 |
Other Indications for DURVALUMAB
Non-small cell lung cancer (3,396)
Hepatocellular carcinoma (1,255)
Small cell lung cancer (1,063)
Bile duct cancer (972)
Non-small cell lung cancer stage iii (840)
Small cell lung cancer extensive stage (660)
Lung neoplasm malignant (641)
Pancreatic carcinoma (584)
Cholangiocarcinoma (444)
Neoplasm malignant (253)
Other Drugs Used for K-ras gene mutation
SOTORASIB (752)
AMG-510 (173)
IRINOTECAN (40)
PANITUMUMAB (36)
CETUXIMAB (29)
PEMBROLIZUMAB (28)
BEVACIZUMAB (19)
DALOTUZUMAB (18)
CARBOPLATIN (17)
FLUOROURACIL (17)