Does DURVALUMAB Cause Adrenal insufficiency? 158 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 158 reports of Adrenal insufficiency have been filed in association with DURVALUMAB (IMFINZI). This represents 0.9% of all adverse event reports for DURVALUMAB.
158
Reports of Adrenal insufficiency with DURVALUMAB
0.9%
of all DURVALUMAB reports
21
Deaths
70
Hospitalizations
How Dangerous Is Adrenal insufficiency From DURVALUMAB?
Of the 158 reports, 21 (13.3%) resulted in death, 70 (44.3%) required hospitalization, and 16 (10.1%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DURVALUMAB. However, 158 reports have been filed with the FAERS database.
What Other Side Effects Does DURVALUMAB Cause?
Death (2,817)
Malignant neoplasm progression (1,330)
Pneumonitis (827)
Radiation pneumonitis (786)
Pyrexia (573)
Diarrhoea (530)
Pneumonia (453)
Dyspnoea (444)
Interstitial lung disease (430)
Off label use (395)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which DURVALUMAB Alternatives Have Lower Adrenal insufficiency Risk?
DURVALUMAB vs DUTASTERIDE
DURVALUMAB vs DUTASTERIDE\TAMSULOSIN
DURVALUMAB vs DUVELISIB
DURVALUMAB vs DYDROGESTERONE
DURVALUMAB vs EBASTINE