Does DURVALUMAB Cause Haematotoxicity? 79 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 79 reports of Haematotoxicity have been filed in association with DURVALUMAB (IMFINZI). This represents 0.5% of all adverse event reports for DURVALUMAB.
79
Reports of Haematotoxicity with DURVALUMAB
0.5%
of all DURVALUMAB reports
15
Deaths
5
Hospitalizations
How Dangerous Is Haematotoxicity From DURVALUMAB?
Of the 79 reports, 15 (19.0%) resulted in death, 5 (6.3%) required hospitalization, and 8 (10.1%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DURVALUMAB. However, 79 reports have been filed with the FAERS database.
What Other Side Effects Does DURVALUMAB Cause?
Death (2,817)
Malignant neoplasm progression (1,330)
Pneumonitis (827)
Radiation pneumonitis (786)
Pyrexia (573)
Diarrhoea (530)
Pneumonia (453)
Dyspnoea (444)
Interstitial lung disease (430)
Off label use (395)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
METHOTREXATE (799)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
Which DURVALUMAB Alternatives Have Lower Haematotoxicity Risk?
DURVALUMAB vs DUTASTERIDE
DURVALUMAB vs DUTASTERIDE\TAMSULOSIN
DURVALUMAB vs DUVELISIB
DURVALUMAB vs DYDROGESTERONE
DURVALUMAB vs EBASTINE