Haematotoxicity: Which Medications Cause It? (7,052 Reports Across 293 Drugs)
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Haematotoxicity has been reported as an adverse event with 293 different drugs in the FDA's FAERS database, with 7,052 total reports. 954 of these reports resulted in death.The drugs most commonly associated with Haematotoxicity are CYCLOPHOSPHAMIDE, DOXORUBICIN, and VINCRISTINE.
7,052
Total Reports
293
Drugs Involved
954
Deaths
1,216
Hospitalizations
52.9 yrs
Average Patient Age
56.2% / 43.8%
Female / Male
Which Drugs Cause Haematotoxicity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CYCLOPHOSPHAMIDE | 1,410 | 1.1% | 202 | 155 | 221 |
| DOXORUBICIN | 1,180 | 1.4% | 183 | 141 | 227 |
| VINCRISTINE | 1,038 | 1.4% | 152 | 107 | 204 |
| RITUXIMAB | 812 | 0.5% | 101 | 139 | 205 |
| CARBOPLATIN | 803 | 1.0% | 97 | 154 | 54 |
| METHOTREXATE | 799 | 0.3% | 107 | 92 | 203 |
| PREDNISONE | 730 | 0.5% | 87 | 93 | 190 |
| CYTARABINE | 701 | 1.6% | 97 | 96 | 131 |
| ETOPOSIDE | 677 | 1.3% | 95 | 92 | 80 |
| CISPLATIN | 668 | 1.4% | 71 | 119 | 57 |
| DEXAMETHASONE | 576 | 0.5% | 87 | 142 | 64 |
| PACLITAXEL | 553 | 0.7% | 72 | 88 | 33 |
| OXALIPLATIN | 470 | 0.8% | 29 | 85 | 47 |
| FLUOROURACIL | 441 | 0.8% | 36 | 67 | 47 |
| CAPECITABINE | 354 | 0.6% | 40 | 54 | 25 |
| GEMCITABINE | 344 | 1.1% | 25 | 79 | 37 |
| BEVACIZUMAB | 319 | 0.4% | 38 | 49 | 21 |
| LEUCOVORIN | 318 | 1.3% | 19 | 22 | 70 |
| LENALIDOMIDE | 306 | 0.1% | 67 | 83 | 17 |
| IFOSFAMIDE | 280 | 1.7% | 42 | 63 | 35 |