Does FLUOROURACIL Cause Haematotoxicity? 441 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 441 reports of Haematotoxicity have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.8% of all adverse event reports for FLUOROURACIL.
441
Reports of Haematotoxicity with FLUOROURACIL
0.8%
of all FLUOROURACIL reports
36
Deaths
67
Hospitalizations
How Dangerous Is Haematotoxicity From FLUOROURACIL?
Of the 441 reports, 36 (8.2%) resulted in death, 67 (15.2%) required hospitalization, and 47 (10.7%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 441 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
METHOTREXATE (799)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
Which FLUOROURACIL Alternatives Have Lower Haematotoxicity Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE