Does METHOTREXATE Cause Haematotoxicity? 799 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 799 reports of Haematotoxicity have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
799
Reports of Haematotoxicity with METHOTREXATE
0.3%
of all METHOTREXATE reports
107
Deaths
92
Hospitalizations
How Dangerous Is Haematotoxicity From METHOTREXATE?
Of the 799 reports, 107 (13.4%) resulted in death, 92 (11.5%) required hospitalization, and 203 (25.4%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 799 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
DEXAMETHASONE (576)
Which METHOTREXATE Alternatives Have Lower Haematotoxicity Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA