ECULIZUMAB for Atypical haemolytic uraemic syndrome: Side Effects & Safety Data
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There are 5,848 adverse event reports in the FDA FAERS database where ECULIZUMAB was used for Atypical haemolytic uraemic syndrome.
Most Reported Side Effects for ECULIZUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Fatigue | 4,858 | 11.0% | 91 | 944 |
| Off label use | 4,228 | 9.6% | 577 | 658 |
| Haemoglobin decreased | 3,028 | 6.9% | 127 | 1,045 |
| Headache | 2,699 | 6.1% | 56 | 700 |
| Death | 2,221 | 5.0% | 2,221 | 540 |
| Pyrexia | 1,948 | 4.4% | 128 | 1,129 |
| Dyspnoea | 1,819 | 4.1% | 97 | 737 |
| Asthenia | 1,732 | 3.9% | 95 | 627 |
| Drug ineffective | 1,644 | 3.7% | 164 | 472 |
| Nausea | 1,579 | 3.6% | 47 | 516 |
| Malaise | 1,562 | 3.5% | 91 | 591 |
| Platelet count decreased | 1,502 | 3.4% | 111 | 659 |
| Haemolysis | 1,476 | 3.3% | 87 | 557 |
| Hospitalisation | 1,345 | 3.0% | 75 | 1,336 |
| Blood lactate dehydrogenase increased | 1,290 | 2.9% | 79 | 420 |
Other Indications for ECULIZUMAB
Paroxysmal nocturnal haemoglobinuria (12,054)
Haemolytic uraemic syndrome (8,500)
Product used for unknown indication (6,808)
Myasthenia gravis (5,715)
Off label use (3,550)
Thrombotic microangiopathy (1,312)
Neuromyelitis optica spectrum disorder (1,097)
C3 glomerulopathy (267)
Transplant rejection (176)
Antiphospholipid syndrome (126)
Other Drugs Used for Atypical haemolytic uraemic syndrome
RAVULIZUMAB-CWVZ (1,121)
RITUXIMAB (16)
RAVULIZUMAB (14)
METHYLPREDNISOLONE (12)
PREDNISONE (12)
MYCOPHENOLATE MOFETIL (7)
ERYTHROPOIETIN (5)