ECULIZUMAB for Transplant rejection: Side Effects & Safety Data
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There are 176 adverse event reports in the FDA FAERS database where ECULIZUMAB was used for Transplant rejection.
Most Reported Side Effects for ECULIZUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Fatigue | 4,858 | 11.0% | 91 | 944 |
| Off label use | 4,228 | 9.6% | 577 | 658 |
| Haemoglobin decreased | 3,028 | 6.9% | 127 | 1,045 |
| Headache | 2,699 | 6.1% | 56 | 700 |
| Death | 2,221 | 5.0% | 2,221 | 540 |
| Pyrexia | 1,948 | 4.4% | 128 | 1,129 |
| Dyspnoea | 1,819 | 4.1% | 97 | 737 |
| Asthenia | 1,732 | 3.9% | 95 | 627 |
| Drug ineffective | 1,644 | 3.7% | 164 | 472 |
| Nausea | 1,579 | 3.6% | 47 | 516 |
| Malaise | 1,562 | 3.5% | 91 | 591 |
| Platelet count decreased | 1,502 | 3.4% | 111 | 659 |
| Haemolysis | 1,476 | 3.3% | 87 | 557 |
| Hospitalisation | 1,345 | 3.0% | 75 | 1,336 |
| Blood lactate dehydrogenase increased | 1,290 | 2.9% | 79 | 420 |
Other Indications for ECULIZUMAB
Paroxysmal nocturnal haemoglobinuria (12,054)
Haemolytic uraemic syndrome (8,500)
Product used for unknown indication (6,808)
Atypical haemolytic uraemic syndrome (5,848)
Myasthenia gravis (5,715)
Off label use (3,550)
Thrombotic microangiopathy (1,312)
Neuromyelitis optica spectrum disorder (1,097)
C3 glomerulopathy (267)
Antiphospholipid syndrome (126)
Other Drugs Used for Transplant rejection
METHYLPREDNISOLONE (968)
RITUXIMAB (615)
TACROLIMUS (477)
HUMAN IMMUNOGLOBULIN G (327)
PREDNISONE (300)
MYCOPHENOLATE MOFETIL (297)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (273)
THYMOCYTE IMMUNE GLOBULIN NOS (173)
BORTEZOMIB (145)
PREDNISOLONE (145)