Does ECULIZUMAB Cause Constipation? 228 Reports in FDA Database

Q: Does ECULIZUMAB cause Constipation?

228 reports of Constipation have been filed with the FDA for ECULIZUMAB, representing 0.5% of all ECULIZUMAB adverse event reports.

Q: How dangerous is Constipation from ECULIZUMAB?

Of 228 reports, 5 (2.2%) resulted in death and 81 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 228 reports of Constipation have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.5% of all adverse event reports for ECULIZUMAB.

228

Reports of Constipation with ECULIZUMAB

0.5%

of all ECULIZUMAB reports

Deaths

Hospitalizations

How Dangerous Is Constipation From ECULIZUMAB?

Of the 228 reports, 5 (2.2%) resulted in death, 81 (35.5%) required hospitalization, and 4 (1.8%) were considered life-threatening.

Is Constipation Listed in the Official Label?

Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for ECULIZUMAB.

What Other Side Effects Does ECULIZUMAB Cause?

Fatigue (4,858) Off label use (4,228) Haemoglobin decreased (3,028) Headache (2,699) Death (2,221) Pyrexia (1,948) Dyspnoea (1,819) Asthenia (1,732) Drug ineffective (1,644) Nausea (1,579)

What Other Drugs Cause Constipation?

LENALIDOMIDE (9,635) NIRAPARIB (4,128) ADALIMUMAB (4,063) SEMAGLUTIDE (4,036) TIRZEPATIDE (3,417) ERENUMAB-AOOE (3,104) MORPHINE (2,979) OXYCODONE (2,747) PALBOCICLIB (2,705) POMALIDOMIDE (2,374)

Which ECULIZUMAB Alternatives Have Lower Constipation Risk?

ECULIZUMAB vs EDARAVONE ECULIZUMAB vs EDETATE ECULIZUMAB vs EDOXABAN ECULIZUMAB vs EDOXABAN TOSILATE ECULIZUMAB vs EFALIZUMAB

ECULIZUMAB Full Profile All Constipation Reports All Drugs Causing Constipation ECULIZUMAB Demographics