Does ESTRADIOL Cause Irritability? 280 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 280 reports of Irritability have been filed in association with ESTRADIOL (Estradiol). This represents 0.9% of all adverse event reports for ESTRADIOL.
280
Reports of Irritability with ESTRADIOL
0.9%
of all ESTRADIOL reports
0
Deaths
15
Hospitalizations
How Dangerous Is Irritability From ESTRADIOL?
Of the 280 reports, 15 (5.4%) required hospitalization, and 2 (0.7%) were considered life-threatening.
Is Irritability Listed in the Official Label?
Yes, Irritability is listed as a known adverse reaction in the official FDA drug label for ESTRADIOL.
What Other Side Effects Does ESTRADIOL Cause?
Product adhesion issue (4,774)
Drug ineffective (4,010)
Off label use (3,238)
Hot flush (2,264)
Wrong technique in product usage process (1,871)
Product quality issue (1,671)
Headache (1,504)
No adverse event (1,493)
Application site pruritus (1,181)
Application site erythema (1,117)
What Other Drugs Cause Irritability?
DULOXETINE (3,554)
LEVOTHYROXINE (1,692)
LEVETIRACETAM (1,067)
ARIPIPRAZOLE (851)
LEVONORGESTREL (796)
RIBAVIRIN (775)
AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE (745)
PREGABALIN (736)
METHYLPHENIDATE (735)
QUETIAPINE (638)
Which ESTRADIOL Alternatives Have Lower Irritability Risk?
ESTRADIOL vs ESTRADIOL CYPIONATE
ESTRADIOL vs ESTRADIOL\LEVONORGESTREL
ESTRADIOL vs ESTRADIOL\NORETHINDRONE
ESTRADIOL vs ESTRADIOL\NORETHINDRONE\RELUGOLIX
ESTRADIOL vs ESTRADIOL\PROGESTERONE