Does ESTRADIOL Cause Migraine? 511 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 511 reports of Migraine have been filed in association with ESTRADIOL (Estradiol). This represents 1.6% of all adverse event reports for ESTRADIOL.
511
Reports of Migraine with ESTRADIOL
1.6%
of all ESTRADIOL reports
4
Deaths
41
Hospitalizations
How Dangerous Is Migraine From ESTRADIOL?
Of the 511 reports, 4 (0.8%) resulted in death, 41 (8.0%) required hospitalization, and 8 (1.6%) were considered life-threatening.
Is Migraine Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ESTRADIOL. However, 511 reports have been filed with the FAERS database.
What Other Side Effects Does ESTRADIOL Cause?
Product adhesion issue (4,774)
Drug ineffective (4,010)
Off label use (3,238)
Hot flush (2,264)
Wrong technique in product usage process (1,871)
Product quality issue (1,671)
Headache (1,504)
No adverse event (1,493)
Application site pruritus (1,181)
Application site erythema (1,117)
What Other Drugs Cause Migraine?
ERENUMAB-AOOE (4,290)
ADALIMUMAB (4,238)
GALCANEZUMAB-GNLM (2,612)
METHOTREXATE (2,532)
ETANERCEPT (2,320)
PREDNISONE (2,203)
APREMILAST (2,154)
INFLIXIMAB (2,137)
RITUXIMAB (1,894)
TOFACITINIB (1,878)
Which ESTRADIOL Alternatives Have Lower Migraine Risk?
ESTRADIOL vs ESTRADIOL CYPIONATE
ESTRADIOL vs ESTRADIOL\LEVONORGESTREL
ESTRADIOL vs ESTRADIOL\NORETHINDRONE
ESTRADIOL vs ESTRADIOL\NORETHINDRONE\RELUGOLIX
ESTRADIOL vs ESTRADIOL\PROGESTERONE