Does ETOPOSIDE Cause Ototoxicity? 121 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 121 reports of Ototoxicity have been filed in association with ETOPOSIDE (Avopef). This represents 0.2% of all adverse event reports for ETOPOSIDE.
121
Reports of Ototoxicity with ETOPOSIDE
0.2%
of all ETOPOSIDE reports
6
Deaths
10
Hospitalizations
How Dangerous Is Ototoxicity From ETOPOSIDE?
Of the 121 reports, 6 (5.0%) resulted in death, 10 (8.3%) required hospitalization, and 2 (1.7%) were considered life-threatening.
Is Ototoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ETOPOSIDE. However, 121 reports have been filed with the FAERS database.
What Other Side Effects Does ETOPOSIDE Cause?
Off label use (6,495)
Febrile neutropenia (5,966)
Disease progression (3,776)
Drug ineffective (3,687)
Neutropenia (3,641)
Thrombocytopenia (3,085)
Product use in unapproved indication (2,774)
Anaemia (2,586)
Pyrexia (2,453)
Sepsis (2,211)
What Other Drugs Cause Ototoxicity?
CISPLATIN (273)
CARBOPLATIN (208)
VINCRISTINE (194)
AMIKACIN (158)
GENTAMICIN (108)
CYCLOSPORINE (105)
VANCOMYCIN (87)
LINEZOLID (82)
TOBRAMYCIN (78)
CYCLOPHOSPHAMIDE (76)
Which ETOPOSIDE Alternatives Have Lower Ototoxicity Risk?
ETOPOSIDE vs ETORICOXIB
ETOPOSIDE vs ETRASIMOD ARGININE
ETOPOSIDE vs ETRAVIRINE
ETOPOSIDE vs EUCALYPTOL\MENTHOL\METHYL SALICYLATE\THYMOL
ETOPOSIDE vs EVEROLIMUS